Research Unit on Cardiovascular and Metabolic Diseases
Situated in downtown Paris, in Pitié-Salpêtrière University Hospital, the research unit UMRS 1166-ICAN is located in Pierre and Marie Curie School of Medicine. Established in 2014 our lab was renewed in 2019 for a 5 new year period, under Inserm and Sorbonne Université tutorships.
It brings together 5 internationally recognized research teams with complementary interests and approaches in genetics, genomics, bioinformatics, molecular and cellular biology, physiology and pharmacology to bear upon cardiovascular and metabolic diseases.
As the primary cause of death in developed countries, cardiovascular and metabolic diseases share pathophysiological characteristics as diet, lifestyle, environment, genetic and epigenetic factors that contribute to disease progression, and are also their initial cause. Therefore interactions between basic and clinical research are critical in understanding them.
ICAN unit research teams are members of the Institute of Cardiometabolism and Nutrition IHU ICAN.
AROME, ANR 2023 Research Project, lead by Elise Balse, Estelle Gandjbakhch and Eric Villard (Teams 1 and 3), selected for phase 2.
Selected for phase 2 AROME, ANR 2023 call for projects, A research project lead by Elise Balse, Estelle Gandjbakhch and Eric Villard (Teams 1 and 3) Abstract Cardiac arrhythmias are a major cause of sudden death, stroke, and heart failure. Recent developments in...
Elise Balse and Camille Blandin – Application de l’analyse protéomique à l’étude du rôle d’une protéine d’échafaudage dans le cardiomyocyte – P3S Platform – Feedback Seminar – Thursday November 10, 2022 – 10:00 am to 12:00 pm – room 115 (91)
P3S Platform - Feedback Seminar Thursday November 10, 2022 – 10 a.m. to 12 p.m. - Room 115 (91) Program 10h00 : Présentation des applications proposées par P3S en génomique et protéomique 10:20 : Pierre-Yves Boëlle (Cinbios, UMS PASS) Présentation du pôle...
Elise BALSE – Spatiotemporal Regulation of Ion Channels in the Cardiomyocyte – 31st Ion Channels Meeting – September 11-14, 2022 – Sète, France
31st Ion Channels Meeting - September 11-14, 2022 - Sète, France Elise Balse, Assistant Professor, Sorbonne University, U1166-Research Unit on Cardiovascular and Cardiometabolism Diseases – Head of Team 3 Molecular and Cellular...
Elise BALSE – Ion Channel Trafficking: Control of Ion Channel Density as a Target for Antiarrhythmics ? – The Ion Channel Regulation Conference, August 14-19, 2022 – Nova Scotia, Canada
The Ion Channel Regulation Conference, August 14-19, 2022, Nova Scotia - Canada Elise BALSE, Assistant Professor, Sorbonne University, U1166-Research Unit on Cardiovascular and Cardiometabolism Diseases - Head of Team 3 Molecular and Cellular Plasticity in...
Camille BLANDIN – CASK is a Key Organizer of Cardiomyocyte Electrical and Structural Polarity – 31st Ion Channels Meeting – September 11-14, 2022 – Sète, France
Camille BLANDIN, PhD Student, UMRS 1166 - Team 3 Elise Balse CASK is a key organizer of cardiomyocyte electrical and structural polarity. Abstract: Although the organization of the cardiomyocyte membrane into functional microdomains directly influences the anisotropic...
S. HATEM – Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference – Eurospace. 2022 Jul 27.
Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference. Renate B Schnabel, Elena Andreassi Marinelli, Elena Arbelo, Giuseppe Boriani, Serge Boveda, Claire M Buckley, A John Camm,...
S. HATEM – Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. Heart Rhythm. 2022 Aug 22;S1547-5271(22)02315-3.
Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. Stef Zeemering, Aaron Isaacs, Joris Winters, Bart...
C. FRERE – 2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19. Lancet Oncol. 2022 Jul;23(7):e334-e347.
Farge D, Frere C, Connors JM, Khorana AA, Kakkar A, Ay C, Muñoz A, Brenner B, Prata PH, Brilhante D, Antic D, Casais P, Guillermo Esposito MC, Ikezoe T, Abutalib SA, Meillon-García LA, Bounameaux H, Pabinger I, Douketis J; 2022 international clinical practice...
Events
Mathieu HAUTEFEUILLE – Progrès et limites de la conception de sinusoïde hépatique in-vitro sur puce : vers la construction de systèmes biomimétiques de culture multicellulaires – IBPS – May 30, 2023 – Bordeaux Room (105)
Professor Hossein ARDEHALI, MD, PhD – Northwestern University, Chicago – Role of Iron in Cardiovascular Diseases – April 28, 2023 – 2:00 pm – Room 329
Franck BOCCARA – CHU Saint-Antoine – UMRS 938-Centre de recherche scientifique Saint-Antoine – Lp(a) and Aortic Valve Stenosis – April 20, 2023 – 12:45 pm – Room 514 (105)
Isabelle DESCHENES-Professor and Chair-Dpt. Physiology and Cell Biology-Heart Failure and Arrhythmia-Ohio State Uni.-Regulation of the Cardiac Sodium Channel Nav1.5 by 14-3-3-March 21, 2023-12:30 pm to 2:00 pm-Room 514 (105)
Marie GIZON – Nouvelle approche thérapeutique dans un modèle cellulaire humain du syndrome de Brugada – March 20, 2023 – 2:00 pm – School of Medicine-Room 505 (105)
Lisa GOTTLIEB – MD, PhD – Univ. of Copenhagen – La fibrillation auriculaire et les veines pulmonaires – February 13, 2023 – 12:30 pm – School of Medicine (105) – Room 514
Santiago VERNIA – Imperial College London – Characterization of RNA Splicing Factors Involved in Metabolic Regulation in the Liver – January 31, 2023 – 12:30 pm – School of Medicine (105) – Bordeaux Room
Alexandre MOTTE – Amplitude de la réponse hypertriglycéridémique postprandiale: conséquences métaboliques et contribution des microARNs – December 14, 2022 – 2:00 pm – Room 510 – School of Medicine (105)
