Research Unit on Cardiovascular and Metabolic Diseases
Situated in downtown Paris, in Pitié-Salpêtrière University Hospital, the research unit UMRS 1166-ICAN is located in Pierre and Marie Curie School of Medicine. Established in 2014 our lab was renewed in 2019 for a 5 new year period, under Inserm and Sorbonne Université tutorships.
It brings together 5 internationally recognized research teams with complementary interests and approaches in genetics, genomics, bioinformatics, molecular and cellular biology, physiology and pharmacology to bear upon cardiovascular and metabolic diseases.
As the primary cause of death in developed countries, cardiovascular and metabolic diseases share pathophysiological characteristics as diet, lifestyle, environment, genetic and epigenetic factors that contribute to disease progression, and are also their initial cause. Therefore interactions between basic and clinical research are critical in understanding them.
ICAN unit research teams are members of the Institute of Cardiometabolism and Nutrition IHU ICAN.
Elise Balse and Camille Blandin – Application de l’analyse protéomique à l’étude du rôle d’une protéine d’échafaudage dans le cardiomyocyte – P3S Platform – Feedback Seminar – Thursday November 10, 2022 – 10:00 am to 12:00 pm – room 115 (91)
P3S Platform - Feedback Seminar Thursday November 10, 2022 – 10 a.m. to 12 p.m. - Room 115 (91) Program 10h00 : Présentation des applications proposées par P3S en génomique et protéomique 10:20 : Pierre-Yves Boëlle (Cinbios, UMS PASS) Présentation du pôle...
Elise BALSE – Spatiotemporal Regulation of Ion Channels in the Cardiomyocyte – 31st Ion Channels Meeting – September 11-14, 2022 – Sète, France
31st Ion Channels Meeting - September 11-14, 2022 - Sète, France Elise Balse, Assistant Professor, Sorbonne University, U1166-Research Unit on Cardiovascular and Cardiometabolism Diseases – Head of Team 3 Molecular and Cellular...
Elise BALSE – Ion Channel Trafficking: Control of Ion Channel Density as a Target for Antiarrhythmics ? – The Ion Channel Regulation Conference, August 14-19, 2022 – Nova Scotia, Canada
The Ion Channel Regulation Conference, August 14-19, 2022, Nova Scotia - Canada Elise BALSE, Assistant Professor, Sorbonne University, U1166-Research Unit on Cardiovascular and Cardiometabolism Diseases - Head of Team 3 Molecular and Cellular Plasticity in...
Camille BLANDIN – CASK is a Key Organizer of Cardiomyocyte Electrical and Structural Polarity – 31st Ion Channels Meeting – September 11-14, 2022 – Sète, France
Camille BLANDIN, PhD Student, UMRS 1166 - Team 3 Elise Balse CASK is a key organizer of cardiomyocyte electrical and structural polarity. Abstract: Although the organization of the cardiomyocyte membrane into functional microdomains directly influences the anisotropic...
S. HATEM – Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference – Eurospace. 2022 Jul 27.
Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference. Renate B Schnabel, Elena Andreassi Marinelli, Elena Arbelo, Giuseppe Boriani, Serge Boveda, Claire M Buckley, A John Camm,...
S. HATEM – Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. Heart Rhythm. 2022 Aug 22;S1547-5271(22)02315-3.
Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. Stef Zeemering, Aaron Isaacs, Joris Winters, Bart...
C. FRERE – 2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19. Lancet Oncol. 2022 Jul;23(7):e334-e347.
Farge D, Frere C, Connors JM, Khorana AA, Kakkar A, Ay C, Muñoz A, Brenner B, Prata PH, Brilhante D, Antic D, Casais P, Guillermo Esposito MC, Ikezoe T, Abutalib SA, Meillon-García LA, Bounameaux H, Pabinger I, Douketis J; 2022 international clinical practice...
N. NEYROUD – Generation of a heterozygous SCN5A knockout human induced pluripotent stem cell line by CRISPR/Cas9 edition. Stem Cell Res. 2022 Apr;60:102680.
Generation of a heterozygous SCN5A knockout human induced pluripotent stem cell line by CRISPR/Cas9 edition. Gizon M, Duboscq-Bidot L, El Kassar L, Bobin P, Ader F, Giraud-Triboult K, Charron P, Villard E, Fontaine V, Neyroud N. Stem Cell Res. 2022 Apr;60:102680....
Events
Chiara MACCHI – Pharm. and Mol. Biology Depart. – Univ. of Milano – Exploring the Role of Classical and Non-Classical Biomarkers in the Context of Atherosclerotic Burden – Nov. 24, 2022 – 12:30 pm to 2:00 pm – room 514 – School of Medicine (105)
Elise Balse and Camille Blandin – Application de l’analyse protéomique à l’étude du rôle d’une protéine d’échafaudage dans le cardiomyocyte – P3S Platform – Feedback Seminar – Thursday November 10, 2022 – 10:00 am to 12:00 pm – room 115 (91)
Jérôme MONTNACH – Arrhythmogenic Right Ventricular Cardiomyoptahies: from Animal Models to Innovative Approaches – Nantes University – October 21 2022 – 12:00 – Room 122 (91)
Cédric LE MAY – Actions extra-hépatiques de PCSK9 & Identification d’un variant de gain de fonction de LIPC – Health Research Institute – Nantes University – Thorax Institute – Team 4 Cardiometabolic Diseases – September 28 2022 – 12:30
Jean-Baptiste PENIGAULT – Resolving Spatial Heterogeneity Using Nanostring’s High Precision and Single-Cell Profiling Platforms – May 20 2022 – 12:30 – Amphi D (91)
Etienne KLEIN – Science and Research: on the Good Use of Doubt – Wednesday May 11 2022 – 6:15 pm – Sorbonne University – Pierre and Marie Curie Campus – Amphi 43
Xavier PRIEUR – Thorax Institute – Inserm-Nantes University – Seipin Deficiency as a Model of Adipocyte Dysfunction – April 21 2022 at noon – Bordeaux Room – School of Medicine (105)
Patrick T. ELLINOR – Genetics and single cell sequencing to identify new therapeutic targets for cardiovascular diseases – Broad Institute – Harvard – March 31 2022 – Amphi E (105) – 2:00 pm
