Events

Fête de la Science – A Coeur Battant – UMRS 1166 Stall – Pierre and Marie Curie Campus – Sorbonne University – October 8, 9, 10

Start date: 8 October 2021

End date: 10 October 2021

Location: Pierre and Marie Curie Campus - Sorbonne University

Scientific Dissemination

ICanBeGREEN 2nd Plenary Meeting – Wednesday October 6 2021 – 12:00 to 1:00 pm – Room TBN

Date: 6 October 2021

Time: 12:00 to 1:00

Location: TBN

IcanBeGreen

M. SERMESANT – Computational Cardiology Group Leader – INRIA – Université de Côte d’Azur – Title TBN – Tuesday October 5 2021 – 12:30 to 2:00 pm

Date: 5 October 2021

Time: 12:30 - 2:00 pm

Location: Videoconference

Monthly Lab Seminar

Journée Impact carbone de la recherche et du numérique : enjeux, estimation et scénarii de réduction – Friday September 24 – 8:50 am to 12:30 pm

Date: 24 September 2021

Time: 8:50 to 12:30

Location: En présentiel (salle de séminaire du bâtiment INRAE C8/IMABS) : inscription gratuite mais obligatoire. Elle est limitée aux 40 premiers inscrits; en visio à ce lien : https://inrae-fr.zoom.us/j/96119075837 (merci de vous connecter au moins 5 mn avant le début des exposés)

IcanBeGreen

ICanBeGreen Infos

Journée Impact carbone de la recherche et du numérique : enjeux, estimation et scénarii de réduction
Friday September 24 – 8:50 am to 12:30 pm

Une initiative de l’INRAE
Infos :www.inrae.fr/evenements/journee-limpact-carbone-recherche-du-numerique-enjeux-estimation-scenarii-reduction

1/ en présentiel (salle de séminaire du bâtiment INRAE C8/IMABS – AUZEVILLE – TOULOUSE) : inscription gratuite mais obligatoire (voir site). Elle est limitée aux 40 premiers inscrits.
2/ en visio à ce lien : https://inrae-fr.zoom.us/j/96119075837 (merci de vous connecter au moins 5 mn avant le début des exposés)

PROGRAMME prévisionnel

8h50-9h00 : Tests visio et accueil
9h00-9h45 : Olivier Berné : Labos 1point5 : réduire l’empreinte environnementale de la recherche
9h45-10h30 : Françoise Berthoud : Calcul numérique : pas si virtuel que ça !
10h30-11h : Pause
11h00-11h50 : Sophie Schbath & Clelia Sirami : MaIAGE : bilan carbone et initiatives écoresponsables / Au-delà du bilan carbone d’unité : identifier les leviers d’actions et les verrous afin de mettre en œuvre des actions à la fois ambitieuses et justes.
11h50-12h30 : Juliette Mignot : Vers une transition bas carbone au LOCEAN

M. PUCEAT – Physiopathology of Cardiac Development – MMG – OCT4-Mediated Inflammation Induces Cell Reprogramming at the Origin of Cardiac Valve Development and Aortic Valve Calcification

Date: 14 September 2021

Time: 12:30 - 14:00

Location: Bordeaux Room - School of Medicine 105 Bd de l'Hôpital 75013 PARIS

Monthly Lab Seminar

Monthly Lab Seminar – September 14 2021 – 12:30 to 2:00 pm – Bordeaux Room (105 bd de l’Hôpital)

Michel Pucéat, Head of Physiopathology of Cardiac Development Team – Marseille Medical Genetics.

Title
OCT4-Mediated Inflammation Induces Cell Reprogramming at the Origin of Cardiac Valve Development and Aortic Valve Calcification

Abstract
Cell plasticity plays a key role in embryos by maintaining the differentiation potential of progenitors. Whether postnatal somatic cells reverse to an embryonic-like naïve state to regain plasticity, and re-differentiate into a cell type leading to a disease re-mains intriguing. Using genetic lineage tracing and single cell-RNA sequencing, we reveal that Oct4 is induced by Nfkb at E9.5 in a subset of mouse endocardial cells originating from the anterior heart forming field at the onset of EMT. These cells are primed to chondro-osteogenic cell fate. We observed OCT4 in adult valvular aortic cells leading to calcification of mouse and human valves and report that calcifying cells originate from the Oct4 embryonic lineage. Genetic deletion of Oct4 in the endocardial cell lineage prevents aortic stenosis and calcification of ApoE-/- mouse valve. We established a novel self-reprogramming Nfkb and Oct4-mediated inflammatory pathway triggering a dose-dependent cell reprogramming mechanism of valve calcification.

NSFA E-CONGRESS 2021 – June 23-24 2021

Start date: 23 June 2021

End date: 24 June 2021

Time: 13:30 to 18:00

Location: Videoconference

Meeting

Nouvelle Société française d’Athérosclérose – E-Congrès 2021 – 23-24 juin 2021
New French Atherosclerosis Society – E-Congress – June 23-24 2021

Free – Mandatory registration

After a white year, the NSFA is organizing this year an e-congress on 23 and 24 June 2021. This conference will take the form of a remote conference with conferences only in the afternoon and presentations poster all day. The conference will be free but will require a registration for which you will receive information and the program in the spring. You can access the conference platform and registration site via this link.

Topics will include endothelium, pediatric hypercholesterolemia and lipid-inflammation.

We will have the pleasure of listening to the lectures of the foreign speakers:
Costantino Iadecola (USA),
Japp van Buul (Nederland),
Oliver Soehnlein (Germany) and
Alan Tall (USA).

C. BEZZINA – Amsterdam U. – Inherited Cardiac Disorders Affecting the Young; Beyond Monogenic Inheritance – June 14 2021

Date: 14 June 2021

Time: 11:00 - 12:30

Location: Video-conference

Monthly Lab Seminar

Monthly Lab Seminar: June 14 2021 – 11:00 to 12:30

Connie Bezzina, University of Amsterdam – Department of Clinical and Experimental Cardiology

Title: Inherited Cardiac Disorders Affecting the Young; Beyond Monogenic Inheritance

Researcher invited by Philippe Charron

ResearchGate link : https://www.researchgate.net%20›%20profile%20›%20Connie-Bezzina-2

ORCID: 0000-0002-0633-3514

Keywords: Inherited cardiovascular disorders, complex cardiovascular diseases

 

S. TALEB – PARCC – Immuno-metabolic Mechanisms of Cardiovascular Diseases – May 18 2021

Date: 18 May 2021

Time: 12:30 - 14:00

Location: TBD according to sanitary conditions

Monthly Lab Seminar

Monthly Lab Seminar: May, 18 2021 – 12:30 to 2:00 pm

Soraya Taleb, U970 Parcc – Immuno-metabolic Mechanisms of Cardiovascular Diseases, invited by Wilfried Le Goff

Title: Role of Tryptophan Metabolism in Cardiometabolic Diseases

Scientific summary
Soraya Taleb, PhD: senior researcher at the French National Health and Medical Research Institute (Inserm) – Parcc – Immuno-metabolic Mechanisms of Cardiovascular Diseases. She is interested in understanding the links between the diet and cardiometabolic complications such as Metabolic Syndrome (MetS) and atherosclerosis.

Researcher ID: K-8176-2017 – ORCID: 0000-0002-6650-619X

Keywords: Cardiometabolism, Atherosclerosis, Obesity

This seminar is reserved for lab members.

SU – Concours ITRF 2021 – 15.02.2021-29.04.2021

Date: 29 April 2021

Recruitment by competitive examination

SORBONNE UNIVERSITE – Concours ITRF 2021 – du 15.02.2021 au 29.04.2021

Calendrier des inscriptions
Les inscriptions seront ouvertes nationalement sur le site du Ministère du jeudi 1er avril à 12H00 au jeudi 29 avril 2021, date de clôture des registres d’inscription et date limite d’envoi des dossiers par voie postale, le cachet de la poste faisant foi.

Monthly Lab Seminar – J.-S. SILVESTRE (PARCC) – Immuno-inflammation et infarctus du myocarde – April 6, 2021 – 12:30

Date: 6 April 2021

Time: 12:30 - 13:30

Location: Videoconference

Monthly Lab Seminar

Monthly Lab Seminar: April, 6 2021 – 12:30 to 1:30 pm

Jean-Sébastien Silvestre, U970 PARCC – Regenerative Therapies for Cardiac and Vascular Diseases

Title: Immunoinflammation and myocardial infarction

Researcher invited by Catherine Pavoine

Scientific summary
Jean-Sébastien Silvestre, PhD: senior research director at the French National Health and Medical Research Institute (Inserm). His work focus on the identification of molecular and cellular mechanisms regulating key events in post-ischemic tissue remodelling with potent revascularization and regenerative therapeutic promise. Since 1995, he is a co-author of 95 original research papers and over 40 reviews or book chapters.

Researcher ID: K-7695-2017; ORCID: 0000-0003-3962-2205

Keywords: Cardiovascular diseases, Ischemia, Regenerative medicine, Inflammation, Stem cells

This seminar is reserved for lab members.

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