Research Unit on Cardiovascular and Metabolic Diseases
Situated in downtown Paris, in Pitié-Salpêtrière University Hospital, the research unit UMRS 1166-ICAN is located in Pierre and Marie Curie School of Medicine. Established in 2014 our lab was renewed in 2019 for a 5 new year period, under Inserm and Sorbonne Université tutorships.
It brings together 5 internationally recognized research teams with complementary interests and approaches in genetics, genomics, bioinformatics, molecular and cellular biology, physiology and pharmacology to bear upon cardiovascular and metabolic diseases.
As the primary cause of death in developed countries, cardiovascular and metabolic diseases share pathophysiological characteristics as diet, lifestyle, environment, genetic and epigenetic factors that contribute to disease progression, and are also their initial cause. Therefore interactions between basic and clinical research are critical in understanding them.
ICAN unit research teams are members of the Institute of Cardiometabolism and Nutrition IHU ICAN.
Ph. CHARRON – Genome-wide association analysis in dilated cardiomy...
Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23....
M. GUERIN – Interleukin-1β and Risk of Premature Death in Patients...
Interleukin-1β and Risk of Premature Death in Patients With Myocardial Infarction Silvain J, Kerneis M, Zeitouni M, Lattuca B, Galier S, Brugier D,...
AUTOMATE – Autophagy-Mediated Control of Tissue-Resident Macrophag...
ANR AAPG 2020 AUTOMATE - Autophagy-mediated control of tissue-resident macrophage maintenance and function Coordinator Vincent Flacher - CNRS -...
EL GAUTIER – Impaired Kupffer Cell Self-Renewal Alters the Liver R...
Tran S, Baba I, Poupel L, Dussaud S, Moreau M, Gélineau A, Marcelin G, Magréau-Davy E, Ouhachi M, Lesnik P, Boissonnas A, Le Goff W, Clausen BE,...
A. KONTUSH – HDL and Reverse Remnant-Cholesterol Transport (RRT): ...
Anatol Kontush HDL and Reverse Remnant-Cholesterol Transport (RRT): Relevance to Cardiovascular Disease Trends Mol Med.2020 Dec;26(12):1086-1100....
SN HATEM – Reactivation of the Epicardium at the Origin of Myocard...
Suffee N, Moore-Morris T, Jagla B, Mougenot N, Dilanian G, Berthet M, Proukhnitzky J, Leprince P, Trégouët DA, Puceat M, Hatem SN. Reactivation of...
TRAFFIC – Sodium Channel Trafficking in Cardiomyocytes
ANR AAPG 2020 TRAFFIC - Sodium channel trafficking in cardiomyocytes The objective of the project is to contribute to improving knowledge on the...
MAESTRIA – Machine Learning and Artificial Intelligence for Early ...
H2020 SC1-BHC-06-2020 call on digital diagnostics The project aims to develop and validate the first integrative diagnostic digital platform for...
Events
M. PUCEAT – Physiopathology of Cardiac Development – MMG – OCT4-Mediated Inflammation Induces Cell Reprogramming at the Origin of Cardiac Valve Development and Aortic Valve Calcification
NSFA E-CONGRESS 2021 – June 23-24 2021
Monthly Lab Seminar – C. BEZZINA – Amsterdam U. – Inherited Cardiac Disorders Affecting the Young; Beyond Monogenic Inheritance – June 14 2021
Monthly Lab Seminar – S. TALEB – PARCC – Immuno-metabolic Mechanisms of Cardiovascular Diseases – May 18 2021
SU – Concours ITRF 2021 – 15.02.2021-29.04.2021
Monthly Lab Seminar – J.-S. SILVESTRE (PARCC) – Immuno-inflammation et infarctus du myocarde – April 6, 2021 – 12:30
Inserm – Concours internes ITA 2021 – Pré-inscription 23.02.2021 au 23.03.2021 – Validation dossier 24.03.2021
ICANBEGREEN – Semaine verte à l’U1166 – U1166 Green Week – March 15-21 2021
