Research Unit on Cardiovascular and Metabolic Diseases
Situated in downtown Paris, in Pitié-Salpêtrière University Hospital, the research unit UMRS 1166-ICAN is located in Pierre and Marie Curie School of Medicine. Established in 2014 our lab was renewed in 2019 for a 5 new year period, under Inserm and Sorbonne Université tutorships.
It brings together 5 internationally recognized research teams with complementary interests and approaches in genetics, genomics, bioinformatics, molecular and cellular biology, physiology and pharmacology to bear upon cardiovascular and metabolic diseases.
As the primary cause of death in developed countries, cardiovascular and metabolic diseases share pathophysiological characteristics as diet, lifestyle, environment, genetic and epigenetic factors that contribute to disease progression, and are also their initial cause. Therefore interactions between basic and clinical research are critical in understanding them.
ICAN unit research teams are members of the Institute of Cardiometabolism and Nutrition IHU ICAN.
W. LE GOFF – Profound systemic alteration of the immune phenotype ...
Profound systemic alteration of the immune phenotype and an immunoglobulin switch in Erdheim-Chester disease in a single-center of 78 patients....
C. PAVOINE – Early Activation of the Cardiac CX3CL1/CX3CR1 Axis De...
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure M Flamant, N Mougenot, E Balse, L Le Fèvre, F Atassi,...
S. NADAUD – Progenitor/Stem Cells in Vascular Remodeling during Pu...
Progenitor/Stem Cells in Vascular Remodeling during Pulmonary Arterial Hypertension France Dierick, Julien Solinc, Juliette Bignard, Florent...
Ph. CHARRON – Genome-wide association analysis in dilated cardiomy...
Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23....
M. GUERIN – Interleukin-1β and Risk of Premature Death in Patients...
Interleukin-1β and Risk of Premature Death in Patients With Myocardial Infarction Silvain J, Kerneis M, Zeitouni M, Lattuca B, Galier S, Brugier D,...
AUTOMATE – Autophagy-Mediated Control of Tissue-Resident Macrophag...
ANR AAPG 2020 AUTOMATE - Autophagy-mediated control of tissue-resident macrophage maintenance and function Coordinator Vincent Flacher - CNRS -...
EL GAUTIER – Impaired Kupffer Cell Self-Renewal Alters the Liver R...
Tran S, Baba I, Poupel L, Dussaud S, Moreau M, Gélineau A, Marcelin G, Magréau-Davy E, Ouhachi M, Lesnik P, Boissonnas A, Le Goff W, Clausen BE,...
A. KONTUSH – HDL and Reverse Remnant-Cholesterol Transport (RRT): ...
Anatol Kontush HDL and Reverse Remnant-Cholesterol Transport (RRT): Relevance to Cardiovascular Disease Trends Mol Med.2020 Dec;26(12):1086-1100....
Events
G. FRANCHINEAU – Apport de la tomographie par impédance électrique pour personnaliser la ventilation mécanique du patient présentant un syndrome de détresse respiratoire… – December 12th 2021 – Room J (105) – 2:00 pm
Coralie SANGENES – Title TBN – STROMAGICS Team Leader – RESTORE Institute – Toulouse – November 30 2021 – 12:30 am to 2:00 pm – Bordeaux Room
Journée annuelle du Comité d’Ethique de l’Inserm – L’Ethique de la Recherche à l’Aune des Crises – Institut Curie ou web – 13 octobre 2021
Fête de la Science – A Coeur Battant – UMRS 1166 Stall 25 – Pierre and Marie Curie Campus – Sorbonne University – October 8, 9, 10
ICanBeGREEN 2nd Plenary Meeting – Wednesday October 6 2021 – 12:00 to 1:00 pm – Room 329
M. SERMESANT – Artificial Intelligence and Personalised Cardiac Modelling: Learning by Heart – Computational Cardiology Group Leader – INRIA – Université de Côte d’Azur – Tuesday October 5 2021 – 12:30 to 2:00 pm
Journée Impact carbone de la recherche et du numérique : enjeux, estimation et scénarii de réduction – Friday September 24 – 8:50 am to 12:30 pm
M. PUCEAT – Physiopathology of Cardiac Development – MMG – OCT4-Mediated Inflammation Induces Cell Reprogramming at the Origin of Cardiac Valve Development and Aortic Valve Calcification
